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Viewing Diseases As Adaptations
An error that is as natural as it is serious
Oct 14 • 
Randolph Nesse

September 2025

Mood disorders are control system failure modes
Not products of specific brain abnormalities
Sep 15 • 
Randolph Nesse
Epistasis Illustrated
to make the concept and formulas make sense
Sep 7 • 
Randolph Nesse

May 2025

ADHD is not an adaptation
But foraging theory is crucial for understanding it
May 26 • 
Randolph Nesse
The Body is not a Machine
This post is adapted from my 2016 essay that inspired the 2025 PNAS Nexus article with Guru Madhavan and Jay Labov on the origins of failure in bodies…
May 22 • 
Randolph Nesse
What is evolutionary medicine?
Understanding why natural selection left us vulnerable to disease can improve health.
May 21 • 
Randolph Nesse
Why constructive engagement is rare
An evolutionary explanation for the great obstacle to science and congeniality
May 18 • 
Randolph Nesse
© 2025 Randolph Nesse
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